KREATiS
Kreatis replacing experimentation for reach - REACH alternative laboratory testing
Kreatis - an alternative to experimentation for REACH - REACH alternative experimentation

Latest News

Watch our new video tutorial on iSafeRat® model to predict aquatic toxicity of mixtures

July 01, 2014

In this 15 minutes video presentation, Dr. Paul THOMAS from KREATiS introduces the iSafeRat® module to predict aquatic toxicity of mixtures. The approach used was to create a three step model:

  1. First a thermodynamic mixture algorithm was prepared which determines the actual concentration of each constituent in the aqueous phase from a given original mixture concentration;
  2. Next, the non-bioavailable phase was accounted for and excluded from the aqueous concentration;
  3. Finally, the new algorithms from the ecotoxicity QSAR were used as above to determine the relative toxicity of each constituent in terms of activity.
share
Follow us on REACH alternative experimentationREACH alternative experimentation
KREATiS, Knowledge & research in environment and toxicology in silico

Knowledge & research in environment and toxicology in silico