OECD QSAR TOOLBOX
AN INTRODUCTION TO REPLACING EXPERIMENTATION USING READ-ACROSS AND QSAR MODELLING
Trainer
Carole CHARMEAU
Trainer
Floriane LARRAS
Trainer
Gaspard LEVET
Prerequisites
For (eco)toxicologists and chemists, risk assessors, regulatory affairs consultants
Courses held at the KREATiS offices, by videoconference or at your premises*.
*Travel expenses to be paid by the client.
1 to 2 days - Duration adapted to the profile and skill level of the client and the objectives to be achieved.
1100€ net per participant and per day of training
OBJECTIVES
► Mastering the OECD QSAR Toolbox interface and functionalities.
► Be able to use the tool to obtain profiling and Read-Across/QSAR predictions for various physicochemical, ecotoxicological and human health endpoints.
► To assess the reliability in predictions derived using the OECD QSAR Toolbox.
► To generate prediction reports for the read-across and QSAR results.
PROGRAMME
Part 1
Basics :
► Introduction to OECD QSAR Toolbox
► Overview of all the tool functionalities
Part 2
Profiling and category formation :
► Introduction to profiling and category formation approaches in the tool
Part 3
Read-Across and QSAR predictions :
► Physicochemical endpoints
► Ecotoxicological and environmental endpoints
► Human health endpoints
► Training participants can choose the endpoints and the chemical structures to be used as case studies
Part 4
Read-Across/QSAR prediction reports :
► Generation of prediction reports which could be used for regulatory purposes
- Digital and paper presentation material
- Free software to download and associated case studies
- Initial knowledge assessment grid
- Pre- and post-training assessment quizzes