Research made in KREATiS

In this section you will find relevant peer reviewed articles, exhibited congress posters and selected magazine articles featuring KREATiS employees and other open source publications that we think you may find useful. We have also made available information on research projects that we have worked on. All the posters are freely available as downloadable pdfs.

R&D projects

KREATiS is regularly involved in R&D projects to increase our understanding of the science and to propose solutions to regulatory challenges using a combination of experimental and in silico approaches. Below is a list of some major projects that we have been, are or hope to be involved in.

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PharmERA

Assessment of prediction of the toxicity of pharmaceuticals in surface water and sediment model organisms, in collaboration with INRAE

Started September 2024
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Do-Q-ToR

Docking & QSAR for Thyroid Receptor

Started September 2022
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CHANCES2

Compartmentalised Hazard Assessment for NCS2

Started September 2020
CosmeBooste

CosmeBooste

Development of SafePAC to assess the risks for human health of the chemicals migrating from the packaging into the cosmetic product.

Duration: 3 years (2021-2024)
COSMETOX

COSMETOX

COSMetic products EcoTOXicity: study ecotoxicity and biodegradability of cosmetic products which are complex substances incorporating many ingredients.

Duration: 3 years (2021-2024)
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DAMIER

Développement et Applications des Modèles Informatiques pour REACH

Duration: 3 years (2014 - 2017)
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CRANCS

Compartmentalised Risk Assessment for Natural Complex Substances

Duration: 18 months (2015 - 2016)
Crack it NC3Rs

NC3Rs CRACK-IT QSARs Mix Challenge

Duration: 12 months(2015 - 2016)

See all KREATiS posters

Classification & Labelling Assessment for Skin Sensitisation (CLASS): AN ADVANCED MULTI-SAR MODEL TO PREDICT SKIN SENSITISATION

G. Levet, M. Darracq-Ghitalla-Ciock, E. Bourgart, F. J. Bauer, E. Ay-Albrecht, Z. Todorov, P. C. Thomas, C. Charmeau-Genevois

Presented by Gaspard Levet at EuroQSAR in Barcelona the 24-26th September 2024

Classification & Labelling Assessment for Skin Sensitisation (CLASS) update: a mechanistic in silico model to predict skin sensitisation potential

G. Levet1 , M. Darracq-Ghitalla-Ciock1 , E. Bourgart1 , F. J. Bauer1 , E. Ay-Albrecht1 , Z. Todorov1 , P. C. Thomas1 , C. Charmeau-Genevois1

Poster presented by Marie Darracq-Ghitalla-Ciock at Eurotox2024 the 8-11th september 2024 in Copenhagen.
 

Contrasting, Characterizing and Predicting the Toxicity and Risk of Natural Complex Substances

Paul Thomas, Floriane Larras

Poster presented by Floriane LARRAS during the SETAC 2024.

Our last articles

Green Swans countering chemical pollution

Leo Posthuma, Michelle Bloor: Writing, Bruno Campos, Ksenia Groh, Annegaaike Leopold, Hans Sanderson, Hanna Schreiber, Christoph Schür, Paul Thomas. 
Integrated Environmental Assessment and Management 2024 — Volume 20, Number 3—pp. 888–893. 

Construction of an In Silico Structural Profiling Tool Facilitating Mechanistically Grounded Classification of Aquatic Toxicants

James W. Firman,* David J. Ebbrell, Franklin J. Bauer, Maria Sapounidou, Geoff Hodges, Bruno Campos, Jayne Roberts, Steve Gutsell, Paul C. Thomas, Mark Bonnell, and Mark T. D. Cronin. Environ. Sci. Technol. 2022, 56, 24, 17805–17814

A scheme to evaluate structural alerts to predict toxicity – Assessing confidence by characterising uncertainties

Mark T.D. Cronin, Franklin J. Bauer, Mark Bonnell, Bruno Campos, David J. Ebbrell, James W. Firman, Steve Gutsell, Geoff Hodges, Grace Patlewicz, Maria Sapounidou, Nicoleta Spînu, Paul C. Thomas, Andrew P. Worth. Regulatory Toxicology and Pharmacology, S0273-2300(22)00136-2. 

Our last other publications

Comment atteindre l'objectif de 100% de plastiques recyclés en 2025 imposés par la loi AGEC ?


click to watch


Ce CosmedTV apporte les réponses aux exigences des nouvelles règlementations environnementales concernant l'incorporation des matériaux recyclés dans les emballages cosmétiques. Qu'elle soit mécanique, chimique ou enzymatique, les 3 techniques de recyclage sont détaillées. La question de la traçabilité, et des interactions contenu/contenant, permettant l'évaluation de la sécurité, sont également des enjeux important du recyclage. Les travaux du consortium Cosmebooste, dont KREATiS fait parti, sont abordés dans ce contexte.

Comment évaluer les interactions contenu/contenant en cosmétique ?

 


Interview de Carole CHARMEAU pour le COSMED TV du 28 juin 2024 qui détaille les objectifs du projet CosmeBooste, les travaux développés par le consortium et les résultats obtenus, avec notamment la plateforme d'évaluation SafePac dédiée à la filière cosmétique développée par KREATiS.

Enquête : vers la fin de l'expérimentation animale ? (2021)

Carole CHARMEAU interviewée par Eléonore Solé, pour FUTURA planète, Janvier 2021