The Eco-NAMs Webinar Series aims to present the most informative and up-to-date science on new approach methodologies (NAMs) for ecotoxicity assessments. Each webinar will consist of presentations by experts followed by a discussion period. The webinar series will provide an open forum for scientists from academia, industry, non-government organisations, regulatory authorities, and other interested parties, including the public, to learn about and discuss various ecotoxicity NAMs topics.
The third webinar in the Eco-NAMs series on the use of NAMs in regulatory ecotoxicology will cover in silico approaches to replace acute fish toxicity. The webinar will be held on Thursday, 28 May, 2026, at 8:00 a.m. EST. Registration and more information are available at https://livewebinar.com/insilicoapproachestoreplaceacutefishtoxicitytesting
The webinar will feature presentations by Anna Lombardo, researcher at Istituto di Ricerche Farmacologiche “Mario Negri” and Paul Thomas, President, Model Developer and Expert Ecotoxicologist at KREATiS.
Ms Lombardo will present a brief introduction to Quantitative Structure Activity Relationships (QSARs) and read-across methods, and then discuss the use of the VEGA (Virtual models for property Evaluation of chemicals within a Global Architecture) HUB tools to assess fish acute toxicity. Through case studies focused on fish acute toxicity that can also be applicable to other endpoints, she will explain the read-across approach used in VERA, the QSAR models available in VEGA, and JANUS, which is a tool for screening and prioritization.
Dr Thomas will discuss the use of
mechanistic QSARs for acute fish toxicity prediction, providing background
information on the published structural alert scheme, mechanism of action (MechoA),
addressing frequently asked questions. His presentation will demonstrate how
the method can link toxic effects between different species and acute and
chronic exposure using a robust mechanistic approach.
The Eco-NAMs webinars are held quarterly. Links to past webinars will be available at https://www.thepsci.eu/eco-nams-webinars/. The webinar series is co-organised by the European Medicines Agency, the Health and Environmental Sciences Institute, the National Institute for Environmental Studies (Japan), PETA Science Consortium International e.V., the US Environmental Protection Agency (US EPA), and the US Food and Drug Administration (US FDA).
Disclaimer: The views expressed in this webinar series are those of the presenters and do not necessarily represent the official views or policies of the US government, the EMA and the NIES. The US FDA, US EPA, EMA and NIES involvement in this webinar series does not imply official endorsement of, or responsibility for, the opinions, ideas, data, products, or services presented.
Guidance for
troubleshooting in LiveWebinar can be found at the bottom of the
Eco-NAMs
webinar series webpage.